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MITOGEN-ACTIVATED PROTEIN KINASES
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DeCS
Descriptor
English
:
Mitogen-Activated Protein Kinases
Descriptor
Spanish
:
Proteínas Quinasas Mitógeno Activadas
Descriptor
Portuguese
:
Proteínas Quinases Ativadas por Mitógeno
Tree Number:
D08.811.913.696.620.682.700.567
D08.811.913.696.620.682.700.646.750
D12.644.360.450
D12.776.476.450
Definition
English
:
A superfamily of
PROTEIN-SERINE-THREONINE KINASES
that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by
phosphorylation
by
MITOGEN-ACTIVATED PROTEIN KINASE KINASES
which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).
Indexing Annotation
English
:
DF: ERKS
See Related
English
:
MAP Kinase Signaling System
History Note
English
:
2000; for EXTRACELLULAR SIGNAL-REGULATED KINASES use CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-1999
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
34450
Unique Identifier:
D020928
Occurrence in VHL
:
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